Steven Watterson

Logo

Computational Cardiovascular Research @ Ulster University

Details of xml schema: SBGN, SBGNML, SBML and CellDesigner.

Atherosclerosis

From Parton et al., Bioinformatics (2018, in press).

Cholesterol metabolism

The cholesterol and vitamin D biosynthesis pathways. From Warren et al., Cells 2021, 10(8), 2007.

The mevalonate arm of the cholesterol biosynthesis pathway. From Benson et al., British Journal of Pharmacology, Volume 174, Issue 23, Pages 4362-4382, 2017.

The pre-Squalene section of the cholesterol biosynthesis pathway. From Mazein et al., Biochemical Pharmacology 86: 1. 56-66 (2013).

The sterol section of the cholesterol biosynthesis pathway (Shunt, Bloch and Kandutsch-Russell arms). From Mazein et al., Biochemical Pharmacology 86: 1. 56-66 (2013).

A simplified model of the cholesterol biosynthesis pathway. From Watterson et al., Biochimie 95, 613-21 (2013).

Flat maps (images)

Regulation and feedback of cholesterol metabolism. From Mazein et al., Nature Precedings

Oxysterol metabolism and regulation. From Giotti, Figshare

Regulation of HMGCR in the mevalonte pathway. From Pappa, Figshare

The Vitamin D3 Synthesis Pathway. From Lu, Figshare